Bringing together ancient Ayurvedic principles and modern scientific knowledge, Aurea Biolabs has created one of the most advanced Liposomal delivery techniques, with Zeal TechnologyTM. This patent-pending technology offers liposomes in a uniquely stable powder form, instead of liquid/suspension, for maximum bio‑efficacy & bio‑availability.
Patent applied for the process titled “A process for the preparation of liposomal powder with bio‑active molecules”, application number - ‘TEMP/E‑1/6253/2018‑CHE’
What is Zeal TechnologyTM?
Liposomes contain phospholipid molecules that protect the active nutrients from digestive enzymes and help carry them into the bloodstream for targeted delivery to the cells. Liposomal products are generally made available in liquid/suspension form, but most products are less stable due to the random nature of the phospholipid bilayer in water. Hydrolysis is also a drawback due to the water emulsion, and the applications of liquid liposomes are limited and cannot be delivered through capsules, in functional foods or dietary supplements. The powder form of liposomes is an alternate solution, but the core structure of the liposome might be destroyed due to the evaporation of water. To overcome this, well-aligned specific carriers can be utilised to retain the core structure of the liposomal bilayer in its powder form, which will help to encapsulate the bioactive molecules effectively. With Zeal TechnologyTM, for the first time ever, active molecules can be delivered by a stable liposomal powder formulation. This powder‑based encapsulation ensures maximum bio‑efficacy, potency and bio‑availability for myriad applications, with the targeted delivery of active ingredients.
What makes ZealTechnology different from other Liposomal products?
What makes Zeal TechnologyTM different from other Liposomal products?
Most liposomal products are available in a liquid or suspension form because phospholipids are stabilised by a water-in-oil emulsion as a vehicle-like compartment for encapsulation. The presence of water, however, can lead to non-uniform phospholipid structures and lower the stability of liposomes. Zeal TechnologyTM, which makes liposomes available in a stable powder form, has been proven to increase encapsulation efficiency, loading capacity and release of the encapsulated bio-ingredients.
How ZealTechnology Works?
How does Zeal TechnologyTM Work?
Zeal TechnologyTM utilises specific carriers from plant materials to formulate a powder form of phospholipid encapsulation. These specific carriers are woven under high-pressure homogenization, followed by the removal of the aqueous phase. Aurea Biolabs has successfully designed and developed a stable Liposomal Curcumin Powder (LCP) using Zeal TechnologyTM to enhance the bio-availability of Curcumin and improve the stability of LCP. Curcumin is an excellent bio‑active constituent for the development of various formulations on account of its well documented range of biological properties. The resulting Liposomal Powder formulation was uniform in shape and size, stable and highly bio‑available.
Applications of Zeal TechnologyTM
Zeal Technology’s unique powder delivery capabilities allow the active bio‑molecules contained in the protective encapsulation to arrive at the target sites with their active ingredients intact. This advanced technology opens up a wide array of opportunities:
Zeta Potential Test
Zeta Potential Test
Zeta potential is an indicator of the stability of liposomal products. Studies show that the powder obtained through Zeal TechnologyTM is liposomal in nature, with nano-sized particles that are spherical, stable and well dispersed. The Zeta potential of conventional phospholipids has been determined to be 25.9 mV, while the Zeta potential value for liposomal curcumin phospholipids is 13.7 mV, clearly indicating superior stability and encapsulation efficiency.